persmedРоссийский журнал персонализированной медициныRussian Journal for Personalized Medicine2782-38062782-3814ФОНД АЛМАЗОВА10.18705/2782-3806-2022-2-6-78-90persmed-104Research ArticleОБЗОРЫREVIEWERSНарушения микробиоты при бактериальном вагинозе и возможности персонализированной терапии заболевания с применением пробиотиков (обзор литературы)Microbiota disorders in bacterial vaginosis and the possibility of personalized therapy of the disease with the use of probiotics (review)КлимовН. А.KlimovN. A.

Климов Николай Анатольевич, к.м.н., ведущий научный сотрудник отдела общей патологии и патофизиологии

Санкт-Петербург

Klimov Nikolai A., PhD, Leading Researcher, Department of General Pathology and Pathophysiology

Saint Petersburg

ШамоваО. В.ShamovaO. V.

Шамова Ольга Валерьевна, д.б.н., член-корреспондент РАН, заместитель директора по научной работе, заведующий отделом общей патологии и патофизиологии Ф; заведующий альтернативных антимикробных биопрепаратов

ул. Академика Павлова, д. 12, Санкт-Петербург, 197022

Shamova Olga V., PhD, corr. member RAS — Deputy Director, Head of the Department of General Pathology and Pathophysiology; Head of the laboratory of alternative antimicrobial biopreparations

Academician Pavlov str., 12, Saint Petersburg, 197022

shamova@iemspb.ruФедеральное государственное бюджетное научное учреждение «Институт экспериментальной медицины», Научный центр мирового уровня «Центр персонализированной медицины»РоссияInstitute of Experimental medicine, World-Class Research Center for Personalized MedicineRussian Federation202221012023267890Copyright © Климов Н.А., Шамова О.В., 20232023Климов Н.А., Шамова О.В.Klimov N.A., Shamova O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://persmed.elpub.ru/jour/article/view/104

В обзоре представлены литературные данные об этиологии и лечении бактериального вагиноза. Бактериальный вагиноз обусловлен сменой протективной микробиоты нижнего отдела женского репродуктивного тракта на патогенную. Данное заболевание имеет широкое распространение в мире, в ряде случаев протекает бессимптомно, но сопровождается осложнениями, к которым относятся хориоамниониты, воспалительные заболевания органов малого таза, цервициты, преждевременные роды. В других случаях это заболевание характеризуется возвратным течением, требующим персонифицированного лечения.

The review presents data on the etiology and treatment of bacterial vaginosis. Bacterial vaginosis is caused by the replacement of a protective microbiota in a lower part of a female reproductive tract with the pathogenic one. This disease is widespread in a world, in some cases it is asymptomatic, but is accompanied by complications, which include chorioamnionitis, inflammatory diseases of the pelvic organs, cervicitis, premature birth. In some cases, the disease is characterized by a recurrent course that requires a personalized treatment.

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The authors declare that there are no conflicts of interest present.