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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">persmed</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал персонализированной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal for Personalized Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2782-3806</issn><issn pub-type="epub">2782-3814</issn><publisher><publisher-name>ФОНД АЛМАЗОВА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2782-3806-2022-2-2-97-103</article-id><article-id custom-type="elpub" pub-id-type="custom">persmed-19</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>REM-ассоциированная брадиаритмия</article-title><trans-title-group xml:lang="en"><trans-title>REM-associated bradyarrhythmia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипенко</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipenko</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Софья Игоревна Осипенко, студент, лаборант-исследователь</p><p>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова»</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИГ сомнологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Sofya I. Osipenko, student, laboratory researcher</p><p>Federal State Budgetary Educational Institution of Higher Education "First St. Petersburg State Medical University named after Academician I. P. Pavlov"</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>NIG of Somnology</p><p>Saint-Petersburg</p></bio><email xlink:type="simple">sofya.osipenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростовцева</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korostovtseva</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Людмила Сергеевна Коростовцева, к. м. н., старший научный сотрудник</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИГ сомнологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Lyudmila S. Korostovtseva, PhD, Senior Researcher</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>NIG of Somnology</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никишкина</surname><given-names>У. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikishkina</surname><given-names>U. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульяна Романовна Никишкина, студент, лаборант-исследователь</p><p>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова»</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИГ сомнологии</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Ulyana R. Nikishkina, student, laboratory researcher</p><p>Federal State Budgetary Educational Institution of Higher Education "First St. Petersburg State Medical University named after Academician I. P. Pavlov"</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>NIG of Somnology</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочкарев</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochkarev</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михаил Викторович Бочкарев, к. м. н., старший научный сотрудник, научный сотрудник</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИГ сомнологии</p><p>НИГ гиперсомний и нарушений дыхания</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Mikhail V. Bochkarev, PhD, Senior Researcher, Researcher</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>NIG of Somnology</p><p>NIH of hypersomnia and respiratory disorders</p><p>Saint-Petersburg</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свиряев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sviryaev</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Владимирович Свиряев, д. м. н., руководитель</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИГ сомнологии</p><p>НИГ гиперсомний и дыхательных расстройств</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Yuri V. Sviryaev, MD, Head</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>NIG of Somnology</p><p>NIH of hypersomnia and respiratory disorders</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint Petersburg State Medical University; Almazov National Medical Research Centre, World-Class Research Centre for Personalized Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Almazov National Medical Research Centre, World-Class Research Centre for Personalized Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2022</year></pub-date><volume>2</volume><issue>2</issue><fpage>97</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Осипенко С.И., Коростовцева Л.С., Никишкина У.Р., Бочкарев М.В., Свиряев Ю.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Осипенко С.И., Коростовцева Л.С., Никишкина У.Р., Бочкарев М.В., Свиряев Ю.В.</copyright-holder><copyright-holder xml:lang="en">Osipenko S.I., Korostovtseva L.S., Nikishkina U.R., Bochkarev M.V., Sviryaev Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://persmed.elpub.ru/jour/article/view/19">https://persmed.elpub.ru/jour/article/view/19</self-uri><abstract><p>   Ночные брадиаритмии представляют особую группу нарушений сердечного ритма, требующих объемной диагностики. В статье представлены случай редко встречающейся аритмии — REM-ассоциированной атриовентрикулярной блокады – и описание нашего подхода к ведению пациента с учетом его индивидуальных особенностей.</p></abstract><trans-abstract xml:lang="en"><p>   Nocturnal bradyarrhythmias represent a special group of cardiac arrhythmias that require volumetric diagnostics. The article presents a case of a rare arrhythmia — REM-associated atrioventricular block and a description of our approach to managing a patient, taking into account his individual characteristics.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>АВ-блокада</kwd><kwd>автономная нервная система</kwd><kwd>брадиаритмия</kwd><kwd>немые инфаркты мозга</kwd><kwd>полисомнография</kwd><kwd>REM-сон</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrioventricular block</kwd><kwd>bradyarrhythmia</kwd><kwd>polysomnography</kwd><kwd>REM-sleep</kwd><kwd>silent brain infarction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Glikson M., Nielsen J. C., Kronborg M. B., Michowitz Y., Auricchio A., Barbash I. 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