<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">persmed</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал персонализированной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal for Personalized Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2782-3806</issn><issn pub-type="epub">2782-3814</issn><publisher><publisher-name>ФОНД АЛМАЗОВА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2782-3806-2023-3-4-106-111</article-id><article-id custom-type="elpub" pub-id-type="custom">persmed-190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Инвазия Endolimax  nana — от диагностики до излечения. Клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Endolimax nana invasion — from diagnosis to cure. A clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тишко</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tishko</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тишко Анна Николаевна - к.м.н., врач клинической лабораторной диагностики лаборатории гематологических и общеклинических методов исследования Отдела лабораторной диагностики; ассистент кафедры лабораторной медицины с клиникой</p><p> ул. Академика Лебедева, д. 4/2, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Tishko Anna N. - PhD, Doctor of Clinical Laboratory Diagnostics, Laboratory of Hematological and General Clinical Research Methods, Department of Laboratory Diagnostics EMERCOM of Russia; Assistant of the Department of Laboratory Medicine with a clinic </p><p>Akademician Lebedeva str., 4/2, Saint Petersburg, 194044</p></bio><email xlink:type="simple">labtishan@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ринарова</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rinarova</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ринарова Полина Викторовна -врач клинической лабораторной диагностики лаборатории гематологических и общеклинических методов исследования Отдела лабораторной диагностики</p><p>ул. Академика Лебедева, д. 4/2, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Rinarova Polina V. - Doctor of Clinical Laboratory Diagnostics, Laboratory of Hematological and General Clinical Research Methods</p><p>Akademician Lebedeva str., 4/2, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рябинкина</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ryabinkina</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рябинкина Лариса Николаевна -врач клинической лабораторной диагностики лаборатории гематологических и общеклинических методов исследования Отдела лабораторной диагностики</p><p>ул. Академика Лебедева, д. 4/2, Санкт-Петербург, 194044</p></bio><bio xml:lang="en"><p>Ryabinkina Larisa N. - Doctor of Clinical Laboratory Diagnostics, Laboratory of Hematological and General Clinical Research Methods, Department of Laboratory Diagnostics EMERCOM of Russia</p><p>Akademician Lebedeva str., 4/2, Saint Petersburg, 194044</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Всероссийский центр экстренной и радиационной медицины имени А. М. Никифорова» Министерства Российской Федерации по делам гражданской обороны, чрезвычайным ситуациям; &#13;
Федеральное государственное бюджетное Учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Nikiforov Russian Center of Emergency and Radiation Medicine; Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Всероссийский центр экстренной и радиационной медицины имени А. М. Никифорова» Министерства Российской Федерации по делам гражданской обороны, чрезвычайным ситуациям и ликвидации последствий стихийных бедствий</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Nikiforov Russian Center of Emergency and Radiation Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2023</year></pub-date><volume>3</volume><issue>4</issue><fpage>106</fpage><lpage>111</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тишко А.Н., Ринарова П.В., Рябинкина Л.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Тишко А.Н., Ринарова П.В., Рябинкина Л.Н.</copyright-holder><copyright-holder xml:lang="en">Tishko A.N., Rinarova P.V., Ryabinkina L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://persmed.elpub.ru/jour/article/view/190">https://persmed.elpub.ru/jour/article/view/190</self-uri><abstract><p>Карликовая амеба — Endolimax nana, относится к наименее описанным непатогенным кишечным простейшим, которые распространены по всему миру. Передача происходит фекально-оральным путем. Основными клиническими проявлениями заражения человека этим простейшим являются симптомы со стороны желудочно-кишечного тракта. Нами описан клинический случай заражения ребенка 8 лет. При проведении копрологического исследования были обнаружены цисты E. Nana, и назначен курс лечения метронидазолом. При контрольном исследовании образцов кала был получен отрицательный результат, клинические проявления исчезли</p></abstract><trans-abstract xml:lang="en"><p>Endolimax nana, is one of the least described non-pathogenic intestinal protozoa that is distributed throughout the world. Transmission occurs by the fecal-oral route. The main clinical manifestations of human infection with this protozoan are symptoms of the gastrointestinal tract. We have described a clinical case of infection in an 8-year-old child. When conducting a coprological study, cysts of E. Nana were found and a course of treatment with metronidazole was prescribed. In the control study of stool samples, a negative result was obtained, clinical manifestations disappeared.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>карликовая амеба</kwd><kwd>метронидазол</kwd><kwd>Endolimax nana</kwd></kwd-group><kwd-group xml:lang="en"><kwd>amoeba</kwd><kwd>Endolimax nana</kwd><kwd>metronidazole</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Constenla M, Padrós F, Palenzuela O. Endolimax piscium sp. nov. (Amoebozoa), causative agent of systemic granulomatous disease of cultured sole, Solea senegalensis Kaup. J Fish Dis. 2014;37:229–40.</mixed-citation><mixed-citation xml:lang="en">Constenla M, Padrós F, Palenzuela O. Endolimax piscium sp. nov. (Amoebozoa), causative agent of systemic granulomatous disease of cultured sole, Solea senegalensis Kaup. J Fish Dis. 2014;37:229–40.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kuenen W, Swellengrebel N. Korte beschrijving van enkelc minder bekendc protozoeo uit denmenschelijkcn darm. Geneesk. Tijdschr v Nederl. 1917:496.</mixed-citation><mixed-citation xml:lang="en">Kuenen W, Swellengrebel N. Korte beschrijving van enkelc minder bekendc protozoeo uit denmenschelijkcn darm. Geneesk. Tijdschr v Nederl. 1917:496.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wenyon C, O’Connor F. London: J. Bale, Sons and Danielsson, Ltd; 1917. Human Intestinal Protozoa in the Near East.</mixed-citation><mixed-citation xml:lang="en">Wenyon C, O’Connor F. London: J. Bale, Sons and Danielsson, Ltd; 1917. Human Intestinal Protozoa in the Near East.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Brug S. Batavia Geneesk: Tydsehr Ned Ind; 1918. Enkele opmerkingen over de nomenclatuur van cenige nieuwere parasieten uit den menschelyken darm; pp. 283– 5.</mixed-citation><mixed-citation xml:lang="en">Brug S. Batavia Geneesk: Tydsehr Ned Ind; 1918. Enkele opmerkingen over de nomenclatuur van cenige nieuwere parasieten uit den menschelyken darm; pp. 283– 5.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dobell C. Researches on the intestinal protozoa of monkeys and man. V. The endolimax of macaques. Parasitology. 1933;25:436–67.</mixed-citation><mixed-citation xml:lang="en">Dobell C. Researches on the intestinal protozoa of monkeys and man. V. The endolimax of macaques. Parasitology. 1933;25:436–67.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dobell C. London: J. Bale and Danielsson; 1919. The Amoebae Living in Man: A Zoological Monograph.</mixed-citation><mixed-citation xml:lang="en">Dobell C. London: J. Bale and Danielsson; 1919. The Amoebae Living in Man: A Zoological Monograph.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Cerva L, Schrottenbaum M, Kliment V. Intestinal parasites: A study of human appendices. Folia Parasitol (Praha). 1991;38:5–9.</mixed-citation><mixed-citation xml:lang="en">Cerva L, Schrottenbaum M, Kliment V. Intestinal parasites: A study of human appendices. Folia Parasitol (Praha). 1991;38:5–9.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Dobell C. Researches on the intestinal protozoa of monkeys and man. XI. The cytology and life-history of endolimax nana. Parasitology. 1943;35:134–58.</mixed-citation><mixed-citation xml:lang="en">Dobell C. Researches on the intestinal protozoa of monkeys and man. XI. The cytology and life-history of endolimax nana. Parasitology. 1943;35:134–58.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Yarinsky A, Burrows R. Atypical nuclei of Endolimax nana in purged stool specimens. Am J Clin Pathol. 1966;46:490–3.</mixed-citation><mixed-citation xml:lang="en">Yarinsky A, Burrows R. Atypical nuclei of Endolimax nana in purged stool specimens. Am J Clin Pathol. 1966;46:490–3.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Moreno P, Perfetti D, Antequera I, Navas P, Acosta M. Contamination of banknotes with enteric parasites in Coro, Falcon state, Venezuela. Bol Malariol Salud Ambient. 2014;54:38–46.</mixed-citation><mixed-citation xml:lang="en">Moreno P, Perfetti D, Antequera I, Navas P, Acosta M. Contamination of banknotes with enteric parasites in Coro, Falcon state, Venezuela. Bol Malariol Salud Ambient. 2014;54:38–46.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Poulsen C, Stensvold C. Systematic review on Endolimax nana: A less well studied intestinal ameba. Trop Parasitol. 2016 Jan-Jun; 6(1): 8–29.</mixed-citation><mixed-citation xml:lang="en">Poulsen C, Stensvold C. Systematic review on Endolimax nana: A less well studied intestinal ameba. Trop Parasitol. 2016 Jan-Jun; 6(1): 8–29.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Zierdt CH. Blastocystis hominis — past and future. Clin Microbiol Rev. 1991;4:61–79.</mixed-citation><mixed-citation xml:lang="en">Zierdt CH. Blastocystis hominis  — past and future. Clin Microbiol Rev. 1991;4:61–79.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Stauffer JQ, Levine WL. Chronic diarrhea related to Endolimax nana: response to treatment with metronidazole. Am J Dig Dis. 1974;19:59–63.</mixed-citation><mixed-citation xml:lang="en">Stauffer JQ, Levine WL. Chronic diarrhea related to Endolimax nana: response to treatment with metronidazole. Am J Dig Dis. 1974;19:59–63.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shah M, Tan C, Rajan D. Blastocystis hominis and Endolimax nana Co-Infection Resulting in Chronic Diarrhea in an Immunocompetent Male. Case Rep Gastroenterol. 2012 May-Aug; 6(2): 358–364</mixed-citation><mixed-citation xml:lang="en">Shah M, Tan C, Rajan D. Blastocystis hominis and Endolimax nana Co-Infection Resulting in Chronic Diarrhea in an Immunocompetent Male. Case Rep Gastroenterol. 2012 May-Aug; 6(2): 358–364</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
