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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">persmed</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал персонализированной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal for Personalized Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2782-3806</issn><issn pub-type="epub">2782-3814</issn><publisher><publisher-name>ФОНД АЛМАЗОВА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2782-3806-2022-2-2-113-120</article-id><article-id custom-type="elpub" pub-id-type="custom">persmed-50</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Проявления нарушений ритма сердца у младенца с синдромом обструктивного апноэ сна, связанного с врожденной аномалией верхних дыхательных путей</article-title><trans-title-group xml:lang="en"><trans-title>Cardiac arrhythmias in an infant with obstructive sleep apnea syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бородин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Borodin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Вячеславович Бородин, врач – детский кардиолог, младший научный сотрудник</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИО неизвестных, редких и генетически обусловленных заболеваний</p><p>197341</p><p>ул. Аккуратова, д. 2</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Alexander V. Borodin, Pediatric Cardiologist, Junior Researcher</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>Research of unknown, rare and genetically determined diseases</p><p>197341</p><p>Akkuratova str., 2</p><p>Saint-Petersburg</p></bio><email xlink:type="simple">Borodin_AV@almazovcentre.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левко</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levko</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Александровна Левко, врач-педиатр</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>отделение педиатрии и медицинской реабилитации № 1</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Tatiana A. Levko, pediatrician</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>Department of Pediatrics and Medical Rehabilitation No. 1</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковальчук</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalchuk</surname><given-names>T. C.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Сергеевна Ковальчук, детский кардиолог, младший научный сотрудник</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>отделение кардиологии и медицинской реабилитации</p><p>НИО неизвестных, редких и генетически обусловленных заболеваний</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Tatiana S. Kovalchuk, Pediatric Cardiologist, Junior Researcher</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>Department of Cardiology and Medical Rehabilitation</p><p>Research of unknown, rare and genetically determined diseases</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Образцова</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Obraztsova</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Игоревна Образцова, д. м. н., профессор</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>Института медицинского образования</p><p>кафедра детских болезней</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Galina I. Obraztsova, MD, Professor</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>Institute of Medical Education</p><p>Department of Children's Diseases</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Александровна Петрова, к. м. н., научный сотрудник, заведующий, доцент</p><p>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова», Научный центр мирового уровня «Центр персонализированной медицины»</p><p>НИО неизвестных, редких и генетически обусловленных заболеваний</p><p>Институт перинатологии и педиатрии</p><p>НИЛ физиологии и патологии новорожденных</p><p>кафедра детских болезней</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Natalia A. Petrova, PhD, Researcher, Head, Associate Professor</p><p>Federal State Budgetary Institution "V. A. Almazov National Medical Research Center", World-class Scientific Center "Center for Personalized Medicine"</p><p>Research of unknown, rare and genetically determined diseases</p><p>Institute of Perinatology and Pediatrics</p><p>NIL Physiology and Pathology of Newborns</p><p>Department of Children's Diseases</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>03</day><month>06</month><year>2022</year></pub-date><volume>2</volume><issue>2</issue><fpage>113</fpage><lpage>120</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бородин А.В., Левко Т.А., Ковальчук Т.С., Образцова Г.И., Петрова Н.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Бородин А.В., Левко Т.А., Ковальчук Т.С., Образцова Г.И., Петрова Н.А.</copyright-holder><copyright-holder xml:lang="en">Borodin A.V., Levko T.A., Kovalchuk T.C., Obraztsova G.I., Petrova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://persmed.elpub.ru/jour/article/view/50">https://persmed.elpub.ru/jour/article/view/50</self-uri><abstract><p>   Представлен клинический случай нарушений ритма сердца у младенца с синдромом обструктивного апноэ сна. В ходе обследования была установлена прямая взаимосвязь аритмий и респираторных событий во время сна. При поиске причины апноэ сна стандартные эндоскопические методики исследования оказались неинформативными, однако использование эндоскопического исследования во время медикаментозно индуцированного сна (sleep-эндоскопия) позволило выявить локализацию обструкции.</p></abstract><trans-abstract xml:lang="en"><p>   A clinical case of heart rhythm disturbances in an infant with obstructive sleep apnea syndrome is presented. During the examination, a direct relationship between arrhythmias and respiratory events during sleep was established. During the search for the cause of sleep apnea, standard endoscopic research techniques were uninformative, but the use of endoscopic examination during drug-induced sleep endoscopy made it possible to identify the localization of obstruction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>апноэ сна у детей</kwd><kwd>кардиореспираторное мониторирование</kwd><kwd>нарушения ритма сердца</kwd><kwd>синдром обструктивного апноэ сна</kwd><kwd>sleep-эндоскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardiorespiratory monitoring</kwd><kwd>heart rhythm disturbances</kwd><kwd>obstructive sleep apnea syndrome</kwd><kwd>sleep apnea in children</kwd><kwd>sleep-endoscopy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке Министерства науки и высшего образования Российской Федерации (Соглашение № 075-15-2022-301 от 20.04.2022)</funding-statement><funding-statement xml:lang="en">The study was carried out with the financial support of the Ministry of Science and Higher Education of the Russian Federation (Agreement No. 075-15-2022- 301 dated 04/20/2022).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Marcus C. 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