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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">persmed</journal-id><journal-title-group><journal-title xml:lang="ru">Российский журнал персонализированной медицины</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal for Personalized Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2782-3806</issn><issn pub-type="epub">2782-3814</issn><publisher><publisher-name>ФОНД АЛМАЗОВА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18705/2782-3806-2022-2-5-16-24</article-id><article-id custom-type="elpub" pub-id-type="custom">persmed-83</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕЙРОХИРУРГИЯ</subject></subj-group></article-categories><title-group><article-title>Анализ типа течения артериовенозных мальформаций головного мозга на основании оценки персонализированных особенностей ангиоархитектоники венозных дренажей</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of the type of course of arteriovenous malformations of the brain on the basis of the evaluation of the personalized features of angioarchitectonics of venous drainages</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамонов</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamonov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-нейрохирург нейрохирургического отделения № 3, научный сотрудник НИЛ хирургии сосудов головного и спинного мозга</p></bio><bio xml:lang="en"><p>Neurosurgeon of Neurosurgical department No. 3, Researcher of the Laboratory for Surgery of the Vessels of the Cerebral and Spinal Cord</p></bio><email xlink:type="simple">mammon820@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожченко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhchenko</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-нейрохирург нейрохирургического отделения № 3, руководитель НИЛ хирургии сосудов головного и спинного мозга</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Neurosurgeon of the Neurosurgical Department No. 3, Chef of Laboratory for Surgery of the Vessels ofthe Cerebral and Spinal Cord</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горощенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Goroshchenko</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-нейрохирург нейрохирургического отделения № 3,старший научный сотрудник НИЛ хирургии сосудовголовного и спинного мозга</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Neurosurgeon of the NeurosurgicalDepartment No.3, Senior Researcher of the Research Laboratory for Surgery of the Vessels of the Cerebral and Spinal Cord</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самочерных</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Samochernykh</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., директор</p></bio><bio xml:lang="en"><p>doctor of medical sciences, director</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский нейрохирургический институт имени профессора А. Л. Поленова» — филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polenov Neurosurgical Research Institute, branch of the Almazov National Medical Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>28</day><month>11</month><year>2022</year></pub-date><volume>2</volume><issue>5</issue><fpage>16</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мамонов Н.А., Рожченко Л.В., Горощенко С.А., Самочерных К.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Мамонов Н.А., Рожченко Л.В., Горощенко С.А., Самочерных К.А.</copyright-holder><copyright-holder xml:lang="en">Mamonov N.A., Rozhchenko L.V., Goroshchenko S.A., Samochernykh K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://persmed.elpub.ru/jour/article/view/83">https://persmed.elpub.ru/jour/article/view/83</self-uri><abstract><p>Актуальность. Артериовенозные мальформации головного мозга являются редко встречаемой врожденной сосудистой патологией. В настоящий момент изучение венозного компонента артериовенозных мальформаций является актуальной темой многих исследований. Большинство авторов считают, что ангиоархитектурные особенности венозного звена артериовенозных мальформаций могут оказывать значительное влияние на оценку естественного течения патологии и определение тактики лечения данных больных. Цель. Провести сравнительный анализ персонифицированных особенностей венозного дренирования артериовенозных мальформаций головного мозга с типами клинического течения. Материалы и методы. Были проанализированы результаты обследования 61 взрослого пациента с артериовенозными мальформациями головного мозга, наблюдавшегося в нейрохирургическом отделении № 3 РНХИ им. проф. А. Л. Поленова в период с 2014 по 2021 гг. Проанализированы половозрастные характеристики и данные нейровизуализации, а также особенности венозного оттока артериовенозных мальформаций. Составлены группы пациентов по типу течения заболевания и проведен сравнительный анализ с характеристиками венозного оттока, а также их особенностями. Соотношение мужчины/женщины составило 1,5/1 (37/24). Преобладали больные моложе 45 лет (77,1 %). По типам клинического течения: геморрагический тип — 18 наблюдений (29,5 %); эпилептический тип — 24 пациента (39,3 %); торпидный тип — 19 больных (31,2 %). Результаты. Выявлена корреляция между глубоким расположением тела мальформации, а также дренированием исключительно в систему глубоких вен и геморрагическим типом течения (р = 0,034), в то время как мужской пол и поверхностная локализация мальформации были более характерны для эпилептического типа (p = 0,01). Торпидный тип течения не имел значимых взаимосвязей с исследуемыми особенностями. Заключение. По нашим данным, анализ персонализированных особенностей венозного дренирования церебральных артериовенозных мальформаций может помочь в оценке клинического течения, что улучшит результаты лечения этих пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Background. Arteriovenous malformations of the brain are a rare congenital vascular pathology. At the moment, the study of the venous component of arteriovenous malformations is a hot topic of many studies. Most authors believe that the angioarchitectural features of the venous link of arteriovenous malformations can have a significant impact on assessing the natural course of the pathology and determining the tactics of treating these patients. Objective. In our work, we conducted a assessment and compared the personalized features of venous drainage of arteriovenous malformations of the brain with the type of clinical course. Design and methods. We analyzed the results of a survey of 61 adult patients with arteriovenous malformations of the brain, observed in the neurosurgical department No. 3 of the RNSI n. a. prof. A. L. Polenov in the period from 2014 to 2021. Gender and age characteristics and neuroimaging data, as well as features of the venous outflow of arteriovenous malformations were analyzed. Groups of patients were composed according to the type of the course of the disease and a personalized analysis was carried out with the characteristics of the venous outflow, as well as their features. The male/female ratio was 1.5/1 (37/24). Patients under 45 years of age prevailed (77.1 %). By types of clinical course: hemorrhagic type — 18 cases (29.5 %); epileptic type — 24 patients (39.3 %); torpid type — 19 patients (31.2 %). Results. A correlation was found between the deep location of the body of the malformation, as well as drainage exclusively into the deep vein system, and the hemorrhagic type of course (p = 0.034), while the male gender and superficial localization of the malformation were more characteristic of the epileptic type (p = 0.01). The torpid flow type did not have significant relationships with the studied features. Conclusion. According to our data, an analysis of the personalized characteristics of venous drainage of cerebral arteriovenous malformations can help in assessing the clinical course, which will improve the treatment outcomes of these patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериовенозная мальформация</kwd><kwd>венозный дренаж</kwd><kwd>тип течения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arteriovenous malformation</kwd><kwd>types of clinical course</kwd><kwd>venous drainage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Redekop G, TerBrugge K, Montanera W, et al. Arterial aneurysms associated with cerebral arteriovenous malformations: classification, incidence, and risk of hemorrhage. J Neurosurg. 1998;89(4):539– 546. DOI:10.3171/jns.1998.89.4.0539.</mixed-citation><mixed-citation xml:lang="en">Redekop G, TerBrugge K, Montanera W, et al. 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