Peculiarities of myelopathic syndrome manifestation in personalized diagnostics of cervical spine lesions

The clinical picture of degenerative-dystrophic diseases of the cervical spine, although directly related to the level of involvement in the pathological process of functionally significant structures of the cervical spine, but also largely depends on the patient’s personalized data and comorbid status. Modern diagnostic methods cannot reliably demonstrate the involvement of these structures in the pathological process. In this regard, continuous research and development of new diagnostic methods for degenerative-dystrophic diseases of the cervical spine is required. Thus, the aim of the study is to identify various clinical and pathogenetic forms of the clinical course degenerative-dystrophic diseases of the cervical spine with myelopathic syndrome. The work is based on the study of clinical manifestations and magnetic resonance imaging of the cervical spine in 158 patients with degenerative-dystrophic diseases of the cervical spine aged 23 to 65 years. Among the patients, women predominated — 59.3 % (93 observations), men accounted for 40.7 % (65 observations). The complex of examination of patients included general clinical, neurological and neuroimaging studies using MRI of the cervical spine.
Damage to one of the functionally significant anatomical structures of the cervical spine occurred in 48.4 % (76 observations). Simultaneous involvement of two or more of these structures in the pathological process was diagnosed in 51.6 % (81 observations). Comparison of neurological symptoms of the disease with magnetic resonance imaging data of the cervical spine makes it possible to diagnose 3 forms of degenerative-dystrophic diseases of the cervical spine: myelic (1.5 %), combined myelo-radicular (38.1 %), combined myelo-radiculo-angiocerebral (6.1 %).
Due to the combination of neurological complications with impaired conduction of the spinal cord with symptoms of compression or irritation of the spinal cord roots and vertebral artery, the clinical manifestations of the disease acquire a significant variety of symptoms, which is always associated with difficulties in diagnosing degenerative-dystrophic diseases of the cervical spine. The identified clinical and radiological criteria of myelic, combined myelo-radicular and combined myelo-radiculo-angiocerebral forms of the course of this pathology The identified clinical and radiological criteria of myelic, combined myelo-radicular and combined myelo-radiculo-angiocerebral forms of the course of this pathology.

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