Clinical case of asystole in a teenager due to vaping. Russian Journal for Personalized Medicine
https://doi.org/10.18705/2782-3806-2025-5-2-166-173
EDN: XLNTCD
Abstract
Contemporary society is witnessing a steady increase in e-cigarette use among youth. Numerous studies have confirmed the negative cardiovascular effects of vaping, including sudden cardiac death. In recent years, the scientific community has been actively investigating the impact of e-cigarettes on various body systems.
This article presents a unique clinical case of asystole due to sinus arrest in an adolescent who regularly used e-cigarettes. This case highlights the serious cardiac risks associated with vaping at a young age.
About the Authors
М. А. ShabaevaRussian Federation
Shabaeva Maria A., Head of the Department of Pediatric Cardiology, Assistant Professor at the Department of Perinatology and Pediatrics at the Institute of Medical Education
2nd line of Vasilyevsky Island, 47, Saint Petersburg, 199004
I. V. Dudina
Russian Federation
Dudina Irina V., Head of the Department of Functional Diagnostics
2nd line of Vasilyevsky Island, 47, Saint Petersburg, 199004
A. Yu. Butsukina
Russian Federation
Butsukina Anastasia Yu., Clinical Resident in Pediatric Cardiology, Department of Perinatology and Pediatrics at the Institute of Medical Education
Saint Petersburg
E. S. Vasichkina
Russian Federation
Vasichkina Elena S., MD, Head of the Scientific Research Center for Unknown, Rare and Genetically Determined Diseases of the World-Class Research Centre for Personalized Medicine, Scientific Director of the Department of Pediatric Cardiology and Medical Rehabilitation, Professor of the Department of Perinatology and Pediatrics at the Institute of Medical Education; Chief freelance specialist - pediatric cardiologist of the North-Western Federal District of the Ministry of Health Of the Russian Federation, pediatrician, pediatric cardiologist of the highest category
Saint Petersburg
References
1. Age-standardized estimates of current tobacco use, tobacco smoking and cigarette smoking. WHO, 11 июня 2020.
2. https://ru.wikipedia.org/wiki/Табакокурени-е_в_России#cite_note-novaya-11
3. Salagai OO, Sakharova GM, Antonov NS. Global Survey of Youth Tobacco Use in the Russian Federation: 2004–2021 World Health Organization, 2024 In Russian Салагай О.О., Сахарова Г.М., Антонов Н.С. Глобальное обследование употребления табака среди молодежи в Российской Федерации: 2004–2021 гг. Всемирная организация здравоохранения, 2024 г..
4. Sakharova GM, Antonov NS. Global survey of tobacco use among youth aged 13–15 years // Medicine. 2016. No. 4. In Russian
5. Tkachenko AV, Slinkova TA, Shipkova LN. A new trend: electronic nicotine delivery systems // Pulse Medical and Pharmaceutical Magazine. 2023;25(4):102–107. In Russian
6. Jiang H, Ahmed CMS, Martin TJ, et al. Chemical and Toxicological Characterization of Vaping Emission Products from Commonly Used Vape Juice Diluents. Chem Res Toxicol. 2020 Aug 17;33(8):2157–2163. DOI: 10.1021/acs.chemrestox.0c00174. Epub 2020 Jul 17. PMID: 32618192.
7. Wold LE, Tarran R, Crotty Alexander LE, et al. American Heart Association Council on Basic Cardiovascular Sciences; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Hypertension; and Stroke Council. Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association. Circ Res. 2022 Jul 22;131(3):e70–e82. DOI: 10.1161/RES.0000000000000544. Epub 2022 Jun 21. PMID: 35726609.
8. Rose JJ, Krishnan-Sarin S, Exil VJ, et al. American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation; Council on Epidemiology and Prevention; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; Council on Peripheral Vascular Disease; Stroke Council; and Council on Arteriosclerosis, Thrombosis and Vascular Biology. Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products: A Scientific Statement From the American Heart Association. Circulation. 2023 Aug 22;148(8):703–728. DOI: 10.1161/CIR.0000000000001160. Epub 2023 Jul 17. PMID: 37458106.
9. Wold LE, Tarran R, Crotty Alexander LE, et al.; AmericanHeartAssociationCouncilonBasicCardiovascular Sciences; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Hypertension; and Stroke Council. Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association. Circ Res. 2022 Jul 22;131(3):e70–e82. DOI: 10.1161/RES.0000000000000544. Epub 2022 Jun 21. PMID: 35726609.
10. Neczypor EW, Mears MJ, Ghosh A, et al. E-Cigarettes and Cardiopulmonary Health: Review for Clinicians. Circulation. 2022 Jan 18;145(3):219–232. DOI: 10.1161/CIRCULATIONAHA.121.056777. Epub 2022 Jan 18. PMID: 35041473; PMCID: PMC8820458.
11. Franzen KF, Willig J, Cayo Talavera S, et al. E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: a randomized, double-blinded pilot study. Vasc Med. 2018;23:419–425. DOI: 10.1177/1358863X18779694.
12. Kelesidis T, Tran E, Arastoo S, et al. Elevated cellular oxidative stress in circulating immune cells in otherwise healthy young people who use electronic cigarettes in a cross-sectional single-center study: implications for future cardiovascular risk. J Am Heart Assoc. 2020;9:e016983. DOI: 10.1161/JAHA.120.016983.
13. Demir V, Hidayet S, Turan Y, et al. Acute effects of electronic cigarette smoking on ventricular repolarization in adults. Afr Health Sci. 2020 Dec;20(4):1793–1799. DOI: 10.4314/ahs.v20i4.33. PMID: 34394241; PMCID: PMC8351847.
14. Ip M, Diamantakos E, Haptonstall K, et al. Tobacco and electronic cigarettes adversely impact ECG indexes of ventricular repolarization: implication for sudden death risk. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1176–H1184. DOI: 10.1152/ajpheart.00738.2019. Epub 2020 Mar 20. PMID: 32196360; PMCID: PMC7346537.
15. Bains S, Garmany R, Neves R, et al. Temporal Association Between Vaping and Risk of Cardiac Events. Mayo Clin Proc. 2024 Feb;99(2):241–248. DOI: 10.1016/j.mayocp.2023.09.017. PMID: 38309936.
16. Jones CA, Wallace MJ, Bandaru P, et al. E-cigarettes and arrhythmogenesis: a comprehensive review of pre-clinical studies and their clinical implications. Cardiovasc Res. 2023 Oct 16;119(12):2157–2164. DOI: 10.1093/cvr/cvad113. PMID: 37517059; PMCID: PMC10578912.
17. Kucera C, Ramalingam A, Srivastava S, et al. Nicotine Formulation Influences the Autonomic and Arrhythmogenic Effects of Electronic Cigarettes. Nicotine Tob Res. 2024 Apr 22;26(5):536–544. DOI: 10.1093/ntr/ntad237. PMID: 38011908; PMCID: PMC11033561.
18. Carll AP, Arab C, Salatini R, et al. E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice. Nat Commun. 2022 Oct 25;13(1):6088. DOI: 10.1038/s41467-022-33203-1. PMID: 36284091; PMCID: PMC9596490.
Review
For citations:
Shabaeva М.А., Dudina I.V., Butsukina A.Yu., Vasichkina E.S. Clinical case of asystole in a teenager due to vaping. Russian Journal for Personalized Medicine. Russian Journal for Personalized Medicine. 2025;5(2):166-173. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-2-166-173. EDN: XLNTCD