Preview

Russian Journal for Personalized Medicine

Advanced search

Description of a clinical case of stomach adenocarcinoma during pregnancy

https://doi.org/10.18705/2782-3806-2024-4-5445-451

EDN: ACBECU

Abstract

The frequency of malignant neoplasms during pregnancy has recently become a usually problem in modern medical practice. On average, 1 in 1,000 women will experience cancer during pregnancy. The most common pregnancy-related cancers include cervical, breast, ovarian, malignant melanoma, malignant lymphomas and leukemia, as well as colon and thyroid cancers. The main factor of late diagnosis and poor treatment results is the non-specificity of the symptoms of the disease in the early stages. The occurrence of difficulty at the diagnostic stage is an underestimation of the indications for conducting a diagnostic search. Signet ring cell carcinoma of the stomach is characterized by an aggressive course, rapid metastasis, and therefore is more often diagnosed in late stages and is a prognostically negative histological variant of stomach cancer. Stomach cancer during pregnancy is estimated to complicate 0.026–0.1 % of all pregnancies In this clinical case, an example of the course of signet ring cell carcinoma of the stomach against the background of pregnancy with dichoric diamniotic twins with increasing protein-energy deficiency is given.

About the Authors

E. Y. Zorina
Almazov National Medical Research Centre
Russian Federation

Zorina Ekaterina Yu. - Ph.D. in Medical Sciences, Oncologist.

Saint Petersburg



A. A. Petoyan
Almazov National Medical Research Centre
Russian Federation

Petoyan Armand A. - The resident of Institute of Medical Education.

Akkuratova str., 2, Saint Petersburg, 197314



A. M. Konova
Almazov National Medical Research Centre
Russian Federation

Konova Alexandra M. – Oncologist.

Saint Petersburg



I. N. Danilov
Almazov National Medical Research Centre
Russian Federation

Danilov Ivan N. - Ph.D. in Medical Sciences, Head of the Department of Theoretical Surgery, Institute of Medical Education.

Saint Petersburg



O. A. Li
Almazov National Medical Research Centre
Russian Federation

Li Olga A. - M.D., Oncologist gynecologist.

Saint Petersburg



E. А. Ulrikh
Almazov National Medical Research Centre; North-Western state medical university named after I.I. Mechnikov
Russian Federation

Ulrikh Elena A. - M.D., Ph.D. in Medical Sciences, Prof., head of Gynecologic oncology and Oncofertility Department of Almazov National Medical Research Centre; prof. of Department of Oncology of North-Western State Medical University named after I. I. Mechnikov.

Saint Petersburg



E. L. Dikareva
Almazov National Medical Research Centre
Russian Federation

Dikareva Elena L. - Ph.D. in Medical Sciences, Oncologist gynecologist.

Saint Petersburg



A. V. Yakubov
Almazov National Medical Research Centre
Russian Federation

Yakubov Andrey V. - Head of Anesthesiology and Intensive care for adults Department.

Saint Petersburg



O. S. Kachanova
Almazov National Medical Research Centre
Russian Federation

Kachanova Olga S. - Student of the Institute of Medical Education Almazov National Medical Research Centre, Department of Faculty Surgery with clinic.

Saint Petersburg



K. A. Samochernykh
Almazov National Medical Research Centre
Russian Federation

Samochernykh Konstantin A. - Doctor of Medical Sciences, Professor of the Russian Academy of Sciences, Director of Polenov Russian Scientific Research Institute of Neurosurgery, Head of the Research Center for Personalized Oncology of World-Class Research Centre for Personalized Medicine.

Saint Petersburg



References

1. Ulrikh E, Kalinina E, Dikareva E, et al. Personalized treatment of malignant tumors during pregnancy. Medicine (Baltimore). 2022 Jul 1;101(26):e29803. DOI: 10.1097/MD.0000000000029803. PMID: 35777052; PMCID: PMC9239643.

2. Kedrova AG, Levakov SA. Oncological diseases in pregnant women. Modern tactics and the main difficulties. Klinicheskaya praktika= Clinical practice. 2014;3:40–45. In Russian

3. Constantin A, Constantin R, Achim F, et al. Pregnancy and Gastric Cancer: A Narrative Review. Diagnostics (Basel). 2023 May 29;13(11):1909. DOI: 10.3390/diagnostics13111909. PMID: 37296761; PMCID: PMC10252424.

4. Aprile G, Basile D, Giaretta R, et al. The Clinical Value of Nutritional Care before and during Active Cancer Treatment. Nutrients. 2021 Apr 5;13(4):1196. DOI: 10.3390/nu13041196. PMID: 33916385; PMCID: PMC8065908.

5. Arends J, Bachmann P, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017 Feb;36(1):11–48. DOI: 10.1016/j.clnu.2016.07.015. Epub 2016 Aug 6. PMID: 27637832.

6. Bullock AF, Greenley SL, McKenzie GAG, et al. Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis. Eur J Clin Nutr. 2020 Nov;74(11):1519–1535. DOI: 10.1038/s41430020-0629-0. Epub 2020 May 4. PMID: 32366995; PMCID: PMC7606134.


Review

For citations:


Zorina E.Y., Petoyan A.A., Konova A.M., Danilov I.N., Li O.A., Ulrikh E.А., Dikareva E.L., Yakubov A.V., Kachanova O.S., Samochernykh K.A. Description of a clinical case of stomach adenocarcinoma during pregnancy. Russian Journal for Personalized Medicine. 2024;4(5):445-451. (In Russ.) https://doi.org/10.18705/2782-3806-2024-4-5445-451. EDN: ACBECU

Views: 104


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2782-3806 (Print)
ISSN 2782-3814 (Online)