Brown or beige adipose tissue – a target for metabolic health therapy?
https://doi.org/10.18705/2782-3806-2025-5-1-6-28
EDN: TZSKZE
Abstract
The search for new ways to solve the problem of obesity is highly relevant, since the effectiveness of obesity treatment worldwide is low. A possible promising target for researchers is brown adipose tissue. Brown adipose tissue is involved in the expenditure of excess energy and the maintenance of metabolic health, unlike white adipose tissue. In the human body, there are 2 subtypes of brown adipose tissue – classic brown and beige. This review attempts to determine whether there are differences in the effects of drugs on these subtypes of brown adipose tissue and in the consequences of activating these subtypes.
About the Authors
T. P. Tuchina
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Tuchina Taisiia P., endocrinologist
Akkuratova str., 2, Saint Petersburg, 197341
Yu. A. Kononova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Kononova Yulia A., laboratory assistant of the Department of Endocrinology
Akkuratova str., 2, Saint Petersburg, 197341
G. G. Zasypkin
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Zasypkin German G., Junior Researcher, Research Laboratory of Prediabetes and Metabolic Disorders, Research Institute of Genetic Risks and Personalized
Prevention of World-Class Research Centre for Personalized Medicine
Akkuratova str., 2, Saint Petersburg, 197341
A. Yu. Babenko
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Babenko Alina Yu., Doctor of Medical Sciences, Head of the Research Institute of Genetic Risks and Personalized Prevention of World-Class Research Centre for Personalized Medicine
Akkuratova str., 2, Saint Petersburg, 197341
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Tuchina T.P., Kononova Yu.A., Zasypkin G.G., Babenko A.Yu. Brown or beige adipose tissue – a target for metabolic health therapy? Russian Journal for Personalized Medicine. 2025;5(1):6-28. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-1-6-28. EDN: TZSKZE
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