A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children
https://doi.org/10.18705/2782-3806-2025-5-1-87-93
EDN: XETWYB
Abstract
To this day, there is no Class I (A) evidence base that could serve as a guideline for the treatment of tumor-associated hydrocephalus in children. Tumors of the posterior cranial fossa (PCF), due to their special interaction with the cerebrospinal fluid pathways, are most often accompanied by the development of hydrocephalus. It is debatable which treatment tactics should be applied correctly: whether to install an external ventricular drainage or a ventriculoperitoneal shunt, whether to perform an endoscopic triventriculostomy, or postpone the procedure of cerebrospinal fluid removal until resection of the tumor. This does not exclude the progression of post-resection hydrocephalus, which occurs in 37 % of cases in the pediatric population.
About the Authors
M. S. Nikolaenko
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Nikolaenko Mikhail S., Candidate of Medical Sciences, Neurosurgeon, neurosurgical department for children № 7
Akkuratova str., 2, Saint Petersburg, 197341
K. A. Samochernykh
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Samochernych Konstantin A., Doctor of Medical Sciences professor of the Russian Academy of Sciences, director of the Polenov Neurosurgical Institute – branch Almazov National Medical Research Centre; Head of the Research Center for Personalized Oncology, World-Class Research Centre for Personalized Medicine
Akkuratova str., 2, Saint Petersburg, 197341
N. K. Samochernykh
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Samochernych Nikita K., neurosurgical department for children № 5
Akkuratova str., 2, Saint Petersburg, 197341
A. Yu. Voevodkina
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Voevodkina Alina Yu., Neurosurgeon, Polenov Neurosurgical Institute – branch of Almazov National Medical Research Centre
Akkuratova str., 2, Saint Petersburg, 197341
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Review
For citations:
Nikolaenko M.S., Samochernykh K.A., Samochernykh N.K., Voevodkina A.Yu. A personalized approach to the treatment of hydrocephalus associated with medulloblastoma in children. Russian Journal for Personalized Medicine. 2025;5(1):87-93. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-1-87-93. EDN: XETWYB
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