Modern methods of diagnosis and treatment of osteosarcoma of the jaw. Review of approaches to surgical intervention and subsequent rehabilitation
https://doi.org/10.18705/2782-3806-2025-5-2-100-111
EDN: AJCXQL
Abstract
This article provides a comprehensive overview of modern approaches to the diagnosis and treatment of osteosarcoma of the mandible. The current methods of instrumental and laboratory diagnostics, including the latest imaging technologies and molecular genetic studies, are considered. Special attention is paid to a multidisciplinary approach to treatment combining surgery with neo- and adjuvant chemotherapy. Modern methods of reconstructive surgery and protocols of postoperative rehabilitation are described in detail. The issues of nutritional support at all stages of treatment, including the peculiarities of enteral nutrition and the specifics of diet therapy for various concomitant diseases of the gastrointestinal tract, are covered in detail. Algorithms for the management of patients in the early and late postoperative period are presented, as well as recommendations for long-term follow-up and prevention of complications. Based on the analysis of modern scientific literature and clinical experience, practical recommendations for optimizing the therapeutic and diagnostic process and improving the effectiveness of rehabilitation measures are formulated.
About the Authors
S. M. Makhanova
Federal State Budgetary Educational Institution of Higher Education “I. N. Ulianov Chuvash
State University”
Russian Federation
Russian Federation
Makhanova Sabina M., 5th-year student, Faculty of Dentistry, Department of Ophthalmology and Otorhinolaryngology
Moskovsky ave., 15, Cheboksary, Chuvash Republic, 428015
D. M. Sakharova
Federal State Budgetary Educational Institution of Higher Education “I. N. Ulianov Chuvash
State University”
Russian Federation
Russian Federation
Sakharova Diana M., 5th-year student, Faculty of Dentistry, Department of Ophthalmology and Otorhinolaryngology
Moskovsky ave., 15, Cheboksary, Chuvash Republic, 428015
A. V. Kolbasov
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Kolbasov Alexey V., 6th-year student, Institute of Medical Education
Saint Petersburg
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Review
For citations:
Makhanova S.M., Sakharova D.M., Kolbasov A.V. Modern methods of diagnosis and treatment of osteosarcoma of the jaw. Review of approaches to surgical intervention and subsequent rehabilitation. Russian Journal for Personalized Medicine. 2025;5(2):100-111. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-2-100-111. EDN: AJCXQL
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