Vaginal microflora in women with infertility: current concepts and research prospects
https://doi.org/10.18705/2782-3806-2025-5-2-136-141
EDN: CJSJIS
Abstract
The vaginal microflora plays a key role in maintaining a woman’s reproductive health. A violation of its composition, known as dysbiosis, can lead to the development of inflammatory processes, infections and infertility. This article examines current data on the role of vaginal microflora in the pathogenesis of infertility, including the mechanisms of dysbiosis’ influence on fertility, embryo implantation, and outcomes of assisted reproductive technologies (ART). Special attention is paid to the relationship between bacterial vaginosis (BV) and chronic inflammatory diseases of the pelvic organs, which can cause structural and functional disorders of the reproductive system. Modern methods for the diagnosis and correction of vaginal dysbiosis, including the use of antibiotics, probiotics, and personalized approaches, are also discussed. The article highlights the need for further research to understand the mechanisms of interaction between the microbiota and reproductive health, which may contribute to the development of new strategies for infertility treatment.
About the Author
P. S. Werner
Chelyabinsk State University
Russian Federation
Russian Federation
Werner Polina S., student at the Faculty of Fundamental Medicine
Chelyabinsk
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Review
For citations:
Werner P.S. Vaginal microflora in women with infertility: current concepts and research prospects. Russian Journal for Personalized Medicine. 2025;5(2):136-141. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-2-136-141. EDN: CJSJIS
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