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Российский журнал персонализированной медицины

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Эпилепсия, ассоциированная с менингиомами головного мозга

https://doi.org/10.18705/2782-3806-2025-5-3-188-211

EDN: TUWQAS

Аннотация

Данная статья посвящена основным вопросам, касающимся развития эпилептических приступов у пациентов с менингиомами головного мозга. Раскрыты генетические аспекты, связанные с формированием менингиомы у больных, и особенности локализации и степени злокачественности опухоли при каждой отдельной геномной подгруппе. Названы также факторы, играющие главную роль в возникновении преди послеоперационных эпилептических приступов. Хирургическая резекция менингиом на данный момент остается решающим фактором в излечении пациентов от инвалидизирующих симптомов. Но также важной темой, затронутой в данной статье, является необходимость в дальнейшем исследовании особенностей назначения противоэпилептической терапии пациентам в пред- и послеоперационном периодах, которые в основном заключаются в правильном установлении дозировки и сроков приема препаратов, что может изменить представление об эффективности купирования эпилептических приступов.

Об авторах

А. В. Василенко
Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия; Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия
Россия

Василенко Анна Владимировна, к.м.н., заведующая учебной частью, доцент кафедры нейрохирургии c клиникой Института медицинского образования; доцент кафедры неврологии им. акад. С. Н. Давиденкова



О. А. Попова
Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия
Россия

Попова Ольга Андреевна, студент 6-го курса лечебного факультета Института медицинского образования



Д. А. Новичкова
Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия
Россия

Новичкова Дарья Андреевна, студент 6-го курса лечебного факультета



Т. И. Пулотова
Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия
Россия

Пулотова Тахмина Иброхимджоновна, студент 6-го курса лечебного факультета



П. С. Мхитарян
Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени В. А. Алмазова» Министерства здравоохранения Российской Федерации, Санкт-Петербург, Россия
Россия

Мхитарян Паруйр Сергеевич, заместитель главного врача по цифровой трансформации



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Василенко А.В., Попова О.А., Новичкова Д.А., Пулотова Т.И., Мхитарян П.С. Эпилепсия, ассоциированная с менингиомами головного мозга. Российский журнал персонализированной медицины. 2025;5(3):188-211. https://doi.org/10.18705/2782-3806-2025-5-3-188-211. EDN: TUWQAS

For citation:


Vasilenko A.V., Popova O.A., Novichkova D.A., Pulotova T.I., Mkhitaryan P.S. Epilepsy associated with brain meningiomas. Russian Journal for Personalized Medicine. 2025;5(3):188-211. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-3-188-211. EDN: TUWQAS

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