Modern approaches to the application of radiation research methods for visualization of the glymphatic system of the brain
https://doi.org/10.18705/2782-3806-2025-5-1-50-57
EDN: UDMJMF
Abstract
The glymphatic system of the brain plays an important role in removing metabolic waste and maintaining the homeostasis of the central nervous system. Disorders of its functioning are associated with the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Modern methods of radiation diagnostics, including contrast-enhanced magnetic resonance imaging (MRI), functional MRI, and diffusion-weighted imaging, allow us to study the dynamics of cerebrospinal fluid flow and glymphatic clearance processes. This article discusses current approaches to the visualization of the glymphatic system, their diagnostic capabilities and prospects for application in clinical practice.
About the Authors
D. A. Beregovskii
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Beregovskii Daniil A., resident of the Department of Radiation Diagnostics and medical imaging with the clinic
Akkuratova str., 2, Saint Petersburg, 197341
Ya. A. Filin
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Filin Yana A., resident of the Department of Radiation Diagnostics and medical imaging with the clinic
Akkuratova str., 2, Saint Petersburg, 197341
A. M. Klimovich
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Klimovich Anastasiya M., resident of the Department of Radiation Diagnostics and medical imaging with the clinic
Akkuratova str., 2, Saint Petersburg, 197341
D. D. Dorohova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Dorohova Dariya D., resident of the Department of Radiation Diagnostics and medical imaging with the clinic
Akkuratova str., 2, Saint Petersburg, 197341
G. E. Trufanov
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Trufanov Gennady E., doctor of medical sciences, professor, head of the department of radiation diagnostics and medical imaging with clinic
Akkuratova str., 2, Saint Petersburg, 197341
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Review
For citations:
Beregovskii D.A., Filin Ya.A., Klimovich A.M., Dorohova D.D., Trufanov G.E. Modern approaches to the application of radiation research methods for visualization of the glymphatic system of the brain. Russian Journal for Personalized Medicine. 2025;5(1):50-57. (In Russ.) https://doi.org/10.18705/2782-3806-2025-5-1-50-57. EDN: UDMJMF
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